Determination and quality evaluation of some imported drugs in Iraqi kurdistan region
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Abstract
Some of important drugs in Kurdistan Region are planned to be determined such as analgesics and antibiotics from different available companies. For the first stages Paracetamol, Aspirin, Chloramphenicol, Ibuprofen and Tetracycline drugs were examined and the real quantities determined were compared with that reported on a commercial labels. Mean recoveries 99.2,95.9,99.2,99 and 102.8 respectively, and have percentage errors (%E) -0.80, -4.07,-0.80, 2.80 and -1.00 respectively and the best companies for these drugs.
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References
1-Koshy,K.T. J. Pharm. Sci., 53, (1964), p 1280.
2-Defabrizio F., J.pharm.Sci57,.(1968), p644.
3-Dibbern H.W. and Scholz G., Arch. Pharm., Berl., 298, (1965), p 175.
4-Caude M., and Le Xuan, P., Chromatographia ,9, (1976) , p 20.
5-Deodhar R.D., Shastri., M.R. and Mehta, R.C., Indian J. Pharm., 38 ,(1976), ,p 18.
6-Gurtoc H.L., and Phillips B.M, J. Pharm. Sci., 62, (1973), p 383.
7-Dolegeal-Vendrely M. and Guernet M; Anlusis, 4 , (1976), p 223.
8-Scemama M., Annls Pharm.Fr., 30, (1972), p 861.
9-Prescott L.E.; J. pharm. Pharmac., 23, (1971), ,p 111.
10-.Martinez J.C and Sagrado S.V; J.Pharm. Biomed. Anal., 7,(10), (1989), p 1165.
11-Kamal M. Mahmouid and Sheler H. Hassan, J. Dohuk Univ Vol.5, No.2 (1987), ,pp 99-105.
12-Kwong T.C. L. Liq. Chrom. 10,(1987), pp 305-21.
13-Gillian P.M. and Mary T.K. anal. Chem. 70, (2009), ,pp 409-414.
14-Nagata T. in oka H.; nakazawa H.; Hayrid K. E .and Macneil L.D. (Editors), Chemical Analysis for Antibiotics used in Agriculture, AoAC International, Arlington, VA,(1995), p 207.
15-Pfening A.P.; Madson M.R.; Roybal, J.E.; Turnipseed, S; and J. Salmon, J. AoAC Int. (1997), in press.
16-Kijak P.j.; J. AoAC Int.77(1994), p 34.
17-Bayo J.; Moreno M.A.; Prieta, J; Diaz Z.; Suarez, G. and Dominguez L.; L. AoAC. Int.77(1994), p 854.
18-Keeukens H.J., Aerts m. M.L.; Traag W.A; Nouws J.F.M.; deRuig W.G. Beek W.M.J., Den Hartog, J.M.PJ.; AOAC Int. 75(1992),p.245.
29-Keeukens H.J.; Beek W.M.J and Aerts M.M,L; J. Chrom. 352 (2010),p 445.
20-Agarwal Y.K; Patel S. Indian J. of Pharm. Sci. Jan-Feb, 52(1), (1990),34-5.
21-Kulichenko S.A. and Fessenko S.O. Anal. Chem. Acta481(1), (2003),pp 149-153.
22-Weiw W., Yux and Ju H.., J. of Chrom. Sci. 42(3), (2004), pp 155-160.
23-Frant J.S. and Patrick S.C J. of Chrom. A. 812 (1998), pp 99-109.
24-Oka H and Putterson, J. AoAc International Arlington, VA, (1995), p 207.
25-Shaikh B. and Moats w.A. J.Chrom.,643(1993),p 369.
26-Barker S.A. and Walker C.C.J. Chrom. 624, (1992), p 195.
27-Nazol L.A., Simonet B.M.; Rios A and Vacarcel M.; Anal. Chem. Acta. 517(1-2),(2004),pp 89-94.
28-Sergios A.H., Meropi M.T., Timotheou P. and Antony C.A. Analyst vol.118, (1993),pp 633-637.
29-Varro E.T., Lynn R.B. and James E.R. (1998), Pharmacognosy,9th ed. Lea Fobiger U.S.A. p 357.
30-Reports and Protocols, National Center for Antibiotic and Insulin Analysis, Food and Drug Administration, Dept. of Health, Washington, DC, (1968).
31-Ragazzi E. and Veronese, J.Chrom. 134 (1977), p 223.
32-Barke S.A. and Walker C.C J. of Chrom. 624, (1992) pp 195-209.
33-Mahrous M.S. and Abdel-Khalek M.M Talanta, 31.(1984), , p 289.
34-Poiger H. and Schlatterb CAnalyst,. 101 (1979), ,p 808.
35-Haroun I. and Khattab F. Indian J. Pharm., 40 (1978), ,p 12.
36-Issam M. A. Shaker, Mouayed Q. Al-Abachi, Yousif J. Azeez, Iraq. J.Sci., vol,41A,No.2, (2000), pp109-121.
37-Zhang S.p., Baeyens V.R.C, Vander B.A. and Vander Weken G., Analyst, Feb. 120 (1995), p 463.
38-Li Z, Feng M.L., Lu J.R., Gong Z.L. and Jiang H.L. Analytical Letters 30(4), (1997), pp 797-807.
39-Han H.Y., He Z.K. and Zeng Y. analytical Science 15(5), (1999), pp 467-470.
41-Kazemifard A.G, Moore D.E. J. Pharm. Biomed. Anal. (1997), pp 689-696.
42-Tanase I.G., David I.G., Radu G.L., Iorulescu E.E., Litescu S, Analusis, 26(4) (1998),, pp 175-179.
43-Di J.,Xu X.,Luo J.,Anal.Lett29(15), .(1996),pp 2691-2700.
44-Li Z. Feng M., Lu J.,Gong Z.,Jiang H., Anal. Lett30, (4) . (1997), pp 797-807.
45-Li Y.M.,Van Schepdael A.,Roet E.,Hoogmertens J.F.,J.Liquid Chrom. Relat. Techno l20,(2), .(1997), pp 273-282.
46-Tjoernelund J., Hansen, S.H., J. Pharm. Biomed. Anal,15,(8), .(1997)pp 1077-1082.
47-Tjornelund J., Hansen S.H.,J. Chrom. A737(2),., (1996), pp 291-300.
48-Chen Y.C., Lin C.E.,J.Chrom.,A802(1), .(1998), pp95 -105.
49-Li Y.M., Van Schepdael A., Roet E. Hoogmartens Biomed.Anal15(8), .(2011),pp 1063-1069.
50-British Pharmacopoeia vol.1., (1993),p 349.