Effect of Urtica dioica leaves and Moringa oleifera leaves and seeds on glucose and lipid Profile in the blood of males albino rats exposed to toxicity by cadmium chloride and lead acetate
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Abstract
The current study in Veterinary Medicine College in kirkuk University and kirkuk hosbital for period from 2-2-2015 end 28-12-2015, and designed to observe and test the preventive and Therapy effects for powder of Urtica dioica leaves and Moringa oleifera leaves and seeds in healthy adult males albino rats that exposed to cadmium chloride (5 mg/kg of body weight) and lead acetate (50 mg/kg of body weight) and the amount of the transaction over the period (30) days on Profile of blood lipids, randomly divided into (18) groups, each group included (5) animals. Giving the powder of Urtica dioica leaves and Moringa oleifera seeds led significant decrease (P˂0.05) in concentrations of TC, TG, LDL-C, VLDL-C and significant increase (P˂0.05) in HDL-C, While administration of Moringa oleifera leaf powder for animal groups to the same previous results, whereas did not show significant differences (p˃0.05) in glucose, TG, HDL-C, malondia-ldehyde (MDA) and VLDL-C all of these in comparison with the normal control group. The groups that given cadmium chloride and lead acetate caused a significant increase in the TG, LDL-C, VLDL-C, malondialdehyde (MDA) and significant decrease in HDL-C in comparison with the normal control group. But compariing of these groups with the groups that administrated only Urtica dioica leaves and Moringa oleifera leaves and seeds led to significant decrease in HDL-C. and a significant increase in the TC, TG, LDL-C, VLDL-C. The groups of animals which treated with the powder of these plants under study before and after of exposed to each of cadmium chloride and lead acetate showed a positive effect on the Profile of blood lipids.
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