Serum Liver enzymes activity and some minerals level in the polycystic ovary patients in Salah Al-Deen governorate
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Abstract
Polycystic ovary syndrome (PCOS) represents a commonly encountered metabolic- endocrinopathy that affects young women all over the world. It is characterized by hyperandrogenism, infertility and menstrual irregularity; as well as by being heterogeneous. PCOS was found to be associated with diabetes, insulin resistance, obesity and metabolic syndrome in large number of patients.
The aim of this study is to investigate the effect of this syndrome and its treatment on several parameters. To do so, 77 blood samples (from women in the reproductive age group) were collected in the private outpatients’ clinics of Salah Al-Din governorate. The samples were divided into three groups (control, untreated PCOS and treated PCOS).
Their age, weight, length, medication history data were collected and biochemical tests were carried out to investigate the levels of liver enzymes (Serum glutamic oxaloacetic transaminase (SGOT), Serum glutamic pyruvic transaminase (SGPT), alkaline phosphatase (ALP) and serum phosphorus and iron. The average age was (26.23 ± 0.73 years) and the average body mass index (BMI) was in the overweight zone (26.57 ± 0.78).
We concluded that liver enzymes showed a trend of decreased levels of ALP and SGPT in the treated PCOS group compared to the control; and the decrease in the level was statistically significant in the ALP but was not significant in the SGPT. There was no significant difference in the SGOT levels.
Serum minerals assessment did not show any difference in the phosphorus level, while iron was lower in the treated group but it wasn’t statistically significant.
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