Evaluation of Number of Virulence Factors and Antibiotic Resistance Patterns of Pseudomonas aeruginosa isolated from wound and burn infections in Samarra city
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Abstract
Wound and burn infections is one of the serious problems that patients suffer from in hospitals, since the bacteria that cause wound and burn infections usually have resistance to most of the commonly used antibiotics.
The current study aimed to isolate and diagnose Pseudomonas aeruginosa from patients with burn and wound infections in Samarra City and to test the sensitivity of the isolates to commonly used antibiotics and the production of virulence factor by these isolates.
Swabs were taken from 110 patients attending Samarra General Hospital and some private medical clinics at Samarra who suffer from wound and burn infections. Twenty two isolates of P. aeruginosa were obtained with an isolation rate of 20%.
Production of some virulence factors by P. aeruginosa were detected, and the percentage was as follows:- The DNase at 0%, haemolysin at 81.8%, lecithinase & lipase at 100%, and urease at 81.8%.
A sensitivity test was conducted for (12) antibiotics, whereby P. aeruginosa gave complete resistance to Erythromycin, Trimethoprim - sulfamethoxazole, and Ceftriaxone, and the bacteria showed that it is susceptible to both Tobramycin antibiotics, and Ciprofloxacin, Levofloxacin, and Imepineme, also showed varying resistance to the other antibiotics.
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