Silver and Cobalt nanoparticles as potential antibacterial agents Staphylococcus aureus isolated from wound infections
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Abstract
The present study aimed to isolate and diagnose S. aureus from patients with wound infection after collecting (100) clinical samples of patients attending Salah Al-din General Hospital from the beginning of April to the end of September 2019 from different wound areas, and to study the effect of silver nanoparticles and cobalt on them. The results of the study showed that the two nanoparticles used have the ability to inhibit growth of S. aureus at different concentrations, The molecular study included the observation of the most important molecular changes at the level of DNA after treatment with nanomaterials, where many variations were observed on the bacteria studied, including these changes the emergence and disappearance of packages of DNA and different numbers when treated with nanomaterials, The results of the study showed that the laboratory rats when infected with S.aureus, appeared after about a week and the symptoms which include; clear skin scaling and hair loss at the site of infection. It is also clear that the recovery time was rapid in group of infected rats which treated with nanomaterials
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