Synthesis of some pyrimidine derivatives from-4- acetyl pyridine
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Abstract
Chalcones compounds(1-4) were prepared from - 4 - acetyl pyridine with different aromatic aldehyde benzaldehyde in the presence of KOH solution .
The compounds (1-4) were reacted with thiourea to give compounds (5-8), with guanidine to give compounds (9-12). and with urea to give the compounds (13-16), in the presence of KOH as abasic.
The prepared compounds were identified using melting point apparatus , F T. IR spectro photo meter and (1H-NMR) spectrometer for some compounds .
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