Symptoms of depression and anxiety among a Sample of Type 2 diabetic patients at Primary Health Care in Erbil city
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Abstract
Background and Objectives: Diabetes mellitus (DM) is exceedingly widespread disease with the highest prevalence in the Middle East countries. Co-existing psychological symptoms affect glycemic control and considered as an important problem in achieving target. The objective of this study was to determine the percentage of depressive and anxiety symptoms among diabetes patients.
Methods: This cross-sectional study was conducted among a sample of 300 adult patients with type 2 diabetes who attended Primary Health Care centers in Erbil City during the period from the 1st of July 2016 to the end of 28th of June 2017. The Patient Health Questionnaire (PHQ9) and Diagnostic and Statistical Manual of Mental Disorders DSM-5 questionnaires has been used as diagnostic tools for depression and anxiety. The glycemic control measured using glycated hemoglobin A1C.
Results: The mean age SD of the sample was 54.79 9.16 years, ranging from 40 to 75 years, the median was 54 years and considerable proportion (44.7%) were of low socio-economic status (SES). Only one quarter of the patients are highly adherent to the treatment. 52.3% of the patients were complaining from anxiety whether mild (28%), moderate (23.3%) or severe (1%). Regarding depression, 58.7% had had depression of different severity. No significant association was detected between anxiety and depression with diabetes control as assessed by glycated hemoglobin A1C (p = 0.932) and (p = 0.220) respectively. The prevalence of depression among those who follow a healthy diet (53.6%) and who practice physical activity (41.4%) was significantly less (p = 0.024).
Conclusion: The study revealed that large percentage of type 2 diabetic patients suffered from anxiety and or depressive symptoms, a results should alert all physicians working in primary health centers to consider these symptoms since they have a direct impact in improving treatment
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References
1. International Diabetes Federation Diabetes Atlas Update 2012. IDF, Brussels, Belgium. Available from: http://www.idf.org/diabetesatlas accessed April (2015)
2. Holman, RR.; Paul, SK.; Bethel, MA.; Matthews, DR. and Neil, HA. (2008). 10-year follow up of intensive glucose control in type 2 diabetes. N Engl J Med. 359:1577-89.
3. Stone, MA.; Charpentier, G.; Doggen, K.; Kuss, O.; Lindblad, U. and Kellner, C. et al.(2013). Quality
of care of people with type 2 diabetes in eight European countries: findings from the Guideline Adherence to Enhance Care (GUIDANCE) study. Diabetes Care. 36(9):2628-38.
4. Inzucchi, SE.; Berganstal, RM.; Buse, JB.; Diamant, M.; Ferrannini, E. and Nauck M. et al. (2015). Management of hyperglycemia in type 2 diabetes: A patient-centered approach. Update to a position statement of the American Diabetes
Association and the European Association for the Study of Diabetes. Diabetes Care. 38:140-9 .
5. Chatterton, H.; Younger, T.; Fischer, A. and Khunti, K. (2012). Risk identification and interventions to prevent type 2 diabetes in adults at high risk: Summary of NICE guidance. BMJ. 345(7867),e4624.
6. Papelbaum, M.; Rodrigo, O.; Coutinho, W.; Kupfer, R.; Zagury, L. and Freitas, S. et al.(2011). Depression, glycemic control and type 2 diabetes. Diabetol Metab syndr. 3:26.
7. Blazer, DG.(2003). Depression in late life: review and commentary, J Gerontol A Biol Sci Med Sci. 58:249-65.
8. Dealing with chronic illnesses and depression. Pub Med.
http://www.webmd.com/depression/guide/chronic-illnesses-depression, Accessed on 27 August (2012).
9. Doraiswamy, P.; Khan, Z.; Donahue, R. and Richard, N.(2002). The spectrum of quality-of-life impairments in recurrent geriatric depression. J Gerontol A Biol Sci Med. Sci. 57:M134-37.
10. Santose, M.; Kawamura, H. and Kassouf, A.(2012). Socioeconomic Conditions and Risk of Mental Depression: An Empirical Analysis for Brazilian Citizens. Hindawi Economics Research International Journal.10.1155/278906.
11. Lustman, P.; Anderson, R.; Freedland, K.; de Groot, M.; Carney, R. and Clouse, R.(2000). Depression and poor glycemic control: a meta-analytic review of the literature. Diabetes Care. 23:934-42.
12. Gross, R.; Olfson, M.; Gameroff, M.; Carasquillo, O.; hea, S. and Feder, A. et al.(2005). Depression and glycemic control in Hispanic primary care patients with diabetes. J Gen Intern med. 2p:460-6.
13. Volpato, S.; Ferrucci, L.; Blaum, C.; Ostic, G.; Cappol, A. and Fried, LP. et al.(2003). Progression of lower-extremity disability in older women with diabetes; the women's health and aging study. Diabetes care. 26:70-5.
14. Vinkers, D.; Gussekloo, J.; Stek, M.; Westendorp, R. and van der mast, R.(2004) Temporal relation between depression and congnitive impairment in old age; prospective population based study. BMJ. 320:881.
15. Robert, D.; Pat, J.; Laura, J. and David, H.(2004). Diabetes, Depression, and Quality of Life. Diabetes Care. 27(5): 1066-70
16. Groot, T.; Doyle, T.; Averyt, J.; Risaliti, C. and Shubroo, J.(2014). Depressive Symptoms and Type 2 Diabetes Mellitus in Rural Appalachia: an 18-Month Follow-Up Study. Int J Psychiatry Med. (48):263-77.
17. Bjorntorp, P.; Holm, G. and Rosmond, R.(1999). Hypothalamic arousal, insulin resistance and type 2 diabetes mellitus. Diabet Med. 16(5):373-83.
18. Kleinridders, A.; Cai, W.; Capellucci, L.; Ghazarian, A.; Collins, W. and Vienberg, S. et al (2015). Insulin resistance in brain alters dopamine
turnover and causes behavioral disorders. PNAS. 112 (11): 3463-8.
19. .Maurer, D. and Darnall, C. (2012). Screaning for depression. Am Fam physician. 2;15;85(2):139-44.
20. Amy, BL.; Nell, K. and Cameron, GS. (2015). Diagnosis and management of generalized anxiety disorder and panic disorder in adults. Am Fam Physician. 1:91(9):617-24.
21. Carmen, H.; Martin, C.; Harry, H.; Mandy, W.; WaiMan, C.; Heung, W.et al. (2014). Abstract 558: The eight-item Morisky Medication Adherence scale (MMAS-8) score was associated with glycaemic control in diabetes patients. Hypertension. 64:A558.
22. American Diabetes Association. Diagnosis and Classification of Diabetes Mellitus. Diabetes Care Jan (2010) 33(suppl):S62-9.
23. Jelinek, JF.; Osman, WM.; Khandoker, AH.; Khalaf, K.; Lee, S. and Almahmeed, W. et al (2017). Clinical profiles, comorbidities and complications of type 2 diabetes mellitus in patients from United Arab Emirates. BMJ. (5):1. 24. Masmoudi, J.; Damak, R.; Zouari, H.; Ouali, U.; Mechri, A. and Zouari, N. et al.(2013). Prevalence and Impact of Anxiety and Depression on Type 2 Diabetes in Tunisian Patients over Sixty Years Old. Depress Res Treat. 10.1155/341782. 25. Zhuang, Q.; Shen, L. and Ji, H. (2017). Quantitative assessment of the bidirectional relationships between diabetes and depression. Oncotarget. 8(14):23389-400. 26. Pan, A.; Lucas, M.; Sun, Q.; van Dam, R.; Franco, O. and Manson, J. et al.(2010). Bidirectional Association between Depression and Type 2 Diabetes in Women. Arch Intern Med. 170(21):1884-91. 27.Kruse, J.; Schmitz, N. and Thefeld, W.(2003). On the association between diabetes and mental disorders in a community sample: results from the German National Health Interview and Examination Survey. Diabetes Care. 26(6):1841-6. 28. Sun, N.; Lou, P.; Shang, Y.; Zhang, P.; Wang, J. and Chang, G. et al.(2016). Prevalence and determinants of depressive and anxiety symptoms in adults with type 2 diabetes in China: a cross-sectional study. BMJ. 6(8):10.1136. 29. Hall, K.; Tambekou, J.; Penn, L. Camara, A.; Balde, N. and Sobngwi, E.(2017). Association between depression, glycaemic control and the prevalence of diabetic retinopathy i n a diabetic population in Cameroon. SAJP. (23):983,10.4102. 30. Tovilla-Zárate, C.; Juárez-RojopI Jimenez, Y.; Jiménez, M.; Vázquez, S. and Bermúdez-Ocaña, D. et al.(2012). Prevalence of Anxiety and Depression among Outpatients with Type 2 Diabetes in the Mexican Population. 7(5). 31. Khuwaja, A.; Lalani, S.; Dhanani, R.; Azam, I.; Rafique, G. and White, F.(2010). Anxiety and depression among outpatients with type 2 diabetes: A
multi-Centre study of prevalence and associated factors. Diabetol Metab Syndr. 20(2):72 32. Rajput, R.; Gehlawat, P.; Gehlan, D.; Gupta, R. and Rajput, M.(2016). Prevalence and predictors of depression and anxiety in patients of diabetes mellitus in a tertiary care center. Indian J Endocrinol Metab. 20(6):746-51. 33. Tan, K.; Chan, G.; Eric, H.; Maria, A.; Norliza, M. and Oun, B. et al.(2015). Depression, anxiety and stress among patients with diabetes in primary care: A cross-sectional study. Malays Fam Physician. 10(2):9-12. 34. Alduraywish, A.; Abdel Fattah, D.; Abd-Eltawab, A.; Al-Ruwili, M.; Alhassan, A. and Alnafe, N. (2017). Depression and Anxiety and Their Correlates in Patients with Diabetes Mellitus in Al-Jouf Region, Saudi Arabia. Scientific and Academic Publishing. 7(2):48-56. 35. Al-Amer, R.; Sobeh, M.; Zayed, A. and Al-Domi, H.(2011). Depression among adults with diabetes in Jordan: risk factors and relationship to blood sugar control. J Diabetes Complications. 25(4):247-52.