The Effect of Fructose Level and Prostate Specific Antigen (PSA) on Sperms Motility in InFertiled Men
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Abstract
The aim of this the study was to evaluate the clinical situations by measuring the concentration of fructose and prostate specific antigen(PSA), as well as studying the causes and risk factors of infertiled men .
Eighty semen samples were collected from patients by mastubation who admitted; AL-Batol hospital laboratories and external clinics in diyala, and blood samples were collected from men who suffered from problems of unhaving children and from healthy peoples control group to examine prostate specific antigen (PSA).
Results showed that there was a significant increase in the concentration of fructose and PSA in the case of azoospermia, oligospermi and Asthnospermia compared with men not inferted
Key word: infertility, semen, Fructose, prostate specific antigen PSA.
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References
1. Gurunath, S., Pandian, Z,. Anderson, R, A,. and Bhattacharya, S. (2011). Defining infertility — a systematic review of prevalence studies. Human Reproduction Update.17, 5: pp. 575–588,
2. Bhushan, S., Schuppe, H., Fijak, M. and Meinhardt, A. (2009). Testicular infection: microorganisms, clinical implications and host-pathogen interaction. J. Reprod. Immunol. PP:1- 4.
3. Turek, P. J. (2008). Male infertility. In: E. A. Tanagho, and J. W. McAninch, ed, Textbook of Smith's General Urology. 7th edition. Mc Graw –Hill .New York, :PP:684-716
4. Kadhem, H.K. and Al-Ani, N.K. (2013). Treatment of Oligozoospermic Patients with a
Formulation of Plant Origin (Speman). Diyala Journal of Medicine. 4(1).
5. Esteves, S. C.(2015). Clinical management of infertile men with nonobstructive azoospermia. Asian J Androl. 17(3):PP: 459–470.
6. Chia, S. E., Tay, S. K. and Lim, S. T. (1998). What constitutes a normal seminal analysis? Semen parameters of 243 fertile men. Hum. Rep.13:PP: 3394-339
7. Lilja H. (1997). Prostate-specific antigen: molecular forms and the human kallikrein gene family British Journal of Urology. 79: (Suppl 1) :PP:44-48.
8. Schaller J., Akujamam K., and Tsuda R., et al. (1987). Isolation, characterization and amino-acid
sequence of γ-seminoprotein, a glycoprotein from human seminal plasma. Eur. J. Biochem. 170 :PP: 111-120.
9. Burtis, C.A. and Ashwood, E.R.;(1994). Teitze Text Book of Clinical Chemistry; 2nd. ed.; W.B. Saunders Company.
10. Van Halbeek H., Gerwig G.J., and Vliegenthart J.F.G., et al.(1985). Occurrence of the Y determinant on the N-glycosidic carbohydrate units of human gamma-seminoprotein Biochem. Biophys. Res. Commun. 131:PP: 507-514
11. Tewari, P.C. and Williams, J.S. (1998). Analytical Characteristics of Seminal Fluid PSA Differ from Those of Serum PSA. Clin. Chem. 44(1) :P: 191
12. Vegvari, A., Rezeli, M., Sihlbom C., Hakkinen, J., Carlsohn, E., Malm, J., Lilja, H., Laurell, T,. Marko - Varga, G. (2012). Molecular microheterogeneity of prostate specific antigen in seminal fluid by mass spectrometry. Clinical Biochemistry,45:PP:331–338
13. Reigman, P.H., Vleitstra, R.J. and Vander, Korput, J.A.;(1989). Characterization of the prostate-specific antigen gene: a novel human kallikrein-like gene. Biochem. Biophys. Res. Commun. 159(1):P:95.
14. Nelson, D.L. and Cox, M.M. (2008). Lehninger principles of Biochemistry. 23th Ed. New York. USA:PP:238-242.
15. Al-Daghistani, H. I., Hamad, A.W. R., Abdel-Dayem, M., Al-Swaifi, M., and AbuZaid, M.(2010). Evaluation of Serum Testosterone, Progesterone,
Seminal Antisperm Antibody, and Fructose Levels among Jordanian Males with a History of Infertility. Biochemistry Research International. Article ID 409640:P:8.
16. Ahmed, Z. , Khan M. S., Khan M. A., ul Haq, A. and ur Rahman, J.(2010). SEMINAL FRUCTOSE IN VARIOUS CLASSES OF INFERTILE PATIENTS. Pak J Physiol;6(1).
17. Buckett, W. M. and Lewis-Jones, D. I. (2002) Fructose concentrations in seminal plasma from men with nonobstructive azoospermia, Archives of Andrology. 48(1), pp. 23–27,.
18. Lu, J.C., Chen, F., Xu, H.R., Yu‐Feng Huang, Y.F., and Lu, N.Q. (2006) Standardization and quality control for determination of fructose in seminal plasma. Journal of Andrology,. 29:PP: 1‐25.
19. Hernandez, J. and Thompson, I.M. (2004). Prostate-specific antigen: a review of the validation of the most commonly used cancer biomarker. Cancer,. 101(5):PP: 894-904.
20. Duskova,K and Vesely, S.(2015). Prostate Specific Antigen. Current clinical application and future prospects. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 159(1):PP:18-26.
21. Borros, M. Arneth, M.S. (2009). Clinical Significance of Measuring Prostate-Specific Antigen. LABMEDICINE. 40 (8).
22. Hussain. N. K., Rzoqi, S. S., Numan, A. W.and Ali, D. T.(2011). A Comparative Study of Fructose,
Zinc and Copper Levels in Seminal Plasma in Fertile and Infertile Men. IRAQI J MED SCI, 9 (1).
23. Khatoon, F., Abdullah, F. E., Mushtaq, M., Batoo, S and Balouch, Z.(2014). Correlation of Fructose with Spermatogenesis. Pinnacle Biochemistry Research, 1 (1), Article ID pbcr_129,:PP: 188-193.
24. Moon, K., Osborn, R.H. and Yannone, M.E. (1970). Relationship of testosterone on to human seminal fructose. Invest Urol ,7,:P:478
25. Mayes, P., (1986). Intermediary metabolism of
fructose, The Amer. J. of clin. nutrition,44.
26. Schoor, R.A. (2002). Prostatitis and male infertility: evidence and links. Curr Urol Rep 3,: PP: 324–329.
27. Zohdy, W., (2009). Clinical parameters that predict successful outcome in men with premature ejaculation and inflammatory prostatitis. J. Sex. Med. 6, :PP:3139–3146.
28. Agarwal. A., Virk, G., Ong, C. and du Plessis, S.S. (2014). Effect of Oxidative Stress on Male Reproduction. World J Mens Health. 32(1):PP: 1–17.
29. Dohle, G.R. (2003). Inflammatory-associated obstructions of the male reproductive tract. Andrologia 35,:PP:321–324.
30. Kullisaar, T., Turk, S., Punab, M. and Mandar, R., (2012). Oxidative stress – causeor consequence of male genital tract disorders? Prostate 72,:PP: 977–983.
31. Ghareeb, D. A. and Sarhan E. M.E.(2014). Role of Oxidative Stress in Male Fertility and Idiopathic Infertility: Causes and Treatment. J Diagn Tech Biomed Anal 2:1.
32. Henkel, R. R. (2011). Leukocytes and oxidative stress: dilemma for sperm function and male fertility. Asian Journal of Andrology,13,:PP: 43–52.
33. Motrich, R. D., Maccioni, M., Molina, R., Tissera, A., Olmedo J., Riera C. M. and Rivero V. E.(2005). Reduced semen quality in chronic prostatitis patients that have cellular autoimmune response to prostate antigens. Human Reproduction 20. 9,:PP: 2567–2572
34. Estrada, L.S., Champion, H.C., Wang, R., Rajasekaran, M., Hellstrom, W.J., Augural, B. and Sikka, S.C. (1997). Effect of tumor necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma) on human sperm motility, viability and motion parameters. Int J Androl 20,:PP:237–242.
35. Schulz, M., Sanchez, R., Soto, L., Risopatron, J., Villegas, J., (2010). Effect of Escherichia coli and its soluble factors on mitochondrial membranepotential, phosphatidylserine translocation, viability, and motility of human spermatozoa. Fertil. Steril. 94,:PP: 619–623.
36. Diemer, T., Huwe, P., Michelmann, H.W., Mayer, F., Schiefer, H.G., Weidner, W.(2000). Escherichia coli-induced alterations of human spermatozoa. An electron microscopy analysis. Int. J. Androl. 23,: PP: 178–186.
37. Fraczek, M., Piasecka, M., Gaczarzewicz, D., Szumala-Kakol, A., Kazienko, A., Lenart, S., (2012). Membrane stability and mitochondrial activ-ity of
human-ejaculated spermatozoa during in vitro experimentalinfection with Escherichia coli, Staphylococcus haemolyticus and Bac-teroides ureolyticus. Andrologia 44,:PP: 315–329.
38. Mazzoli, S., Cai, T., Addonisio, P., Bechi, A., Mondaini, N., and Bartoletti, R. (2010). Chlamydia trachomatis infection is related to poor semen quality in young prostatitis patients. Eur. Urol. 57, :PP:708–714.
39. Sunanda, P., Panda B., Dash C., Padhy, R. N., Routray, P.(2014). Effect of age and abstinence on semen quality: A retrospective study in a teaching hospital. Asian Pacific Journal of Reproduction; 3(2): PP: 134-141.
40. Gosalvez, J., Gonzalez-Martinez, M., Lopez-Fernndez, C., Fernandez, J.L., Sanchez-Martin, P.(2011). Shorter abstinence decreases sperm deoxyribonucleic acid fragmentation in ejaculate. Fertil Steril 96:PP:6-1083.
41. Sircar, S. (2008). Sperm transport and fertilization: Principles of medical physiology. Germany: Thieme Medical Publishers :PP: 562-569.
42. Bjorndahl, L., Mortimer, D., Cristopher, L.B.R., Castilla, J.A., Menkveld, R.(2010). Basic physiology: A practical guide to basic laboratory andrology.
Cambridge: Cambridge University Press.:PP: 5-31.
43. Wiener-Megnazi, Z., Auslender, R., Dirnfeld, M. (2012). Advanced paternal age and reproductive outcome. Asian Journal of Andrology 14:PP: 69-76.
44. Sartorius,G. and Nieschlag, E.(2010). Paternal age and reproduction. Human Reproduction Update 16,:PP: 65-79.
45. Sampson, N., Untergrasser, G. and Berger, P. (2007). The aging male reproductive tract. J Pathol; 211:PP: 206-218.
46. Desai, N., Sabanegh, E., Kim, T and Agarwal, A. (2010). Free radical theory of aging: implications in male infertility. Review Article. Urology 75 (1): 14-19.
47. Sharma, R., Agarwal, A, Rohra, V. K., Assidi M., Abu-Elmagdand, M. Turki, R. F.(2015). Effects of increased paternal age on sperm quality, reproductive outcome and associated epigenetic risks to offspring. Sharma et al. Reproductive Biology and Endocrinology, 13:35.