Effect of Bay leaf (Laurus nobilis L.) and its isolated (flavonoids and glycosides) on the lipids profile in the local Iraqi female rabbits
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Abstract
The present study aimed to explain the effect of Bay leaf and its isolated flavonoids and glycosides on the levels of TC, TG, HDL-C, LDL-C and VLDL-C in the local Iraqi female rabbits. Isolation of flavonoids and glycosides from Bay leaf were carried out, the study design included four groups (n=6): Control group-C fed with standard pellet diet; group1-G1 orally administrated daily dose 100 mg/ml/kg of Bay leaf crude for 30 days; group2-G2 orally administrated daily dose 50 mg/ml/kg of isolated flavonoids for 30 days; group3-G3 orally administrated daily dose 12.5 mg/ml/kg of isolated glycosides for 30 days. TC, TG and HDL-C were determined by enzymatic colorimetric method. The results showed that oral administration of Bay leaf and its isolated flavonoids and glycosides reduced levels of TC, TG, LDL-C and VLDL-C compared to control, therefore Bay leaf useful agent in reducing hyperlipidemia.
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