The effect of Cinnamomum zeylanicum plant extracts and Albendazole drug in mice Balb/c infected experimentally with Hydatid cysts and follow some Histological and Physiological changes
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Abstract
The present study included the influence of aqueous and alcoholic extract of Cinnamomum zeylanicum and Albendazole drug in albino mice infected experimentally with Hydatid cysts belong to the parasite Echinococcus granulosus, The doses of alcoholic and aqueous extracts of Cinnamomum zeylanicum were 500 mg/ kg/day as a single treatedable dose, while albendazole drug was given as a single dose 15 mg / kg / day.
The results of the study showed positive influence of each C. zeylanicum extracts and albendazole drug in decreasing lipid profiles (Cholesterol and Triglycerides) concentration and increase of HDL-C concentration compared with the positive control group, which showed the increase of lipid profiles concentration compared with the negetive control group. The effect of alcoholic and aqueous extracts of C. zeylanicum and albendazole drug on Spleen and Liver tissues, which was seminormal form of Spleen, Liver and Lung tissues of infected mice. Abnormal form of Spleen and Liver tissues of infected mice (positive control) and not treated with aqueous and alcoholic extracts of C. zeylanicum and albendazole drug.
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