Study of Some Biochemical Parameters Related to Heart Function in Ascending and Descending Effort

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Dhiaa Kasim Al-Khayat
Luay Abed Al-Helaly
Hadeel Tariq Al-Taee

Abstract

This research is carried out to study the effect of ascending and descending effort on some biochemical parameters related to heart function which include: Arterial natriuretic hormone, angiotensin II, sodium, potassium, lactate dehydrogenase, creatine kinase, aspartate aminotransferase, adiponectin, lipase, triglycerides, free fatty acid, lipooxygenase and myeloperoxidase . The major samples included (15) of the track and field players participating in Mosul university team of middle-distance runners .


The results showed a significant increase for ascending directly post-effort test compared to pre-effort test in: sodium, lactate dehydrogenase, triglycerides and myeloperoxidase and significant decrease in: aspartate aminotransferase, lipase and lipooxygenase.


The results revealed significant increase for descending post-effort directly test compared with pre-effort test in the levels of sodium, potassium, lactate dehydrogenase and triglycerides significant decrease in: lipase, free fatty acids and lipooxygenase.


Moreover the results, showed significant increase for ascending effort  test compared with descending effort test in levels: potassium and aspartate aminotransferase and significant decrease for myeloperoxidase .


The study concluded the need to give the current examination of physical effort ascending and descending for the early detection of heart patients.

Article Details

How to Cite
Dhiaa Kasim Al-Khayat, Luay Abed Al-Helaly, & Hadeel Tariq Al-Taee. (2023). Study of Some Biochemical Parameters Related to Heart Function in Ascending and Descending Effort. Tikrit Journal of Pure Science, 22(12), 47–54. https://doi.org/10.25130/tjps.v22i12.930
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References

1-Hall, J. E. (2011). Textbook of Medical Physiology.

20th. Ed. Saunders, Elsevier, USA. P.109

3-Fox, S. I.(2006). Human physiology. Athed. Mc

Graw Hill, USA.p.444

5-Burtis, C. A., Ashwood, E. R., Bruns, D.E.(2012).

"Tietz Textbook of Clinical Chemistry and Molecular

Diagnostics". By Saunders, an imprint of Elsevier

Inc. USA. pp.356, 368, 356-36.

6-Bishop, M. L., Fody, E. P., Schoeff, L. (2000)

.Clinical Chemistry. principle and correlation

:procedures . 5th. .ed., Lipincott Williams and

Walkins. Philadelphia , p (180-220) .

7-Hillmann, G., Beyer, G., Klin, Z. (1967).

Determination of potassium concentration .Chem.

Clinic. Biochem . 5 : 93.

8-Klin,Z., Klin,U.(1972). Enzymetic reaction for

determination of lactic dehydrogenase. Biochemistry

J.,10:182-187.

9-Sanhai, W.R., Christenson, R.H.(2003). Cardiac

and muscle disease. Clinical Chemistry: Theory,

Analysis, Correlation, 4th Ed., Kaplan, L.A, Pesce,

A.J., Kazmierczak, S.C., (Mosby Inc. eds St. Louis

USA), (2003), 566 and appendix.

10-Winkler, U.K., Stuckmam M. (1979). Glycogen,

hyaluronate, and sorne other polysaccharides greatly

enhance the formation of exolipase by Serratia

marcescens. J. Bacteriol., 138:663-670.

11-Fossati, P., Preencipe, L. (1982). Serum

triglycerides determined colorimetrically with an

enzyme that produces hydrogen peroxide. Clin.

Chem. 28(10): 2077.

12-Shastry, B.S., Rao, M.R. (1975). Studies on

lipoxygenase from rice bran. Cereal Chemistry,

52(5):597-603.

13-Kumar, P., pai, K., Pandey, H.P., Sundar, S.

(2002). NADH – oxidase, and myeloperoxidase

activity of visceral leishmaniasis patients. J. Med.

Microbiol. 51, 832-836.

14-Hinton, P. R. (2004). "Statistics Explained". 2nd

Edition by Routledge. printed in the USA and

Canada. pp.85,125.

16-Berg J. M., Tymoczko J. L., Stryer L. (2007).

"Biochemistry" W. H. Freeman and Company". New

York, USA. pp.138,139,145,146,149, 685, 906

17-Nelson, D. L. and Cox, M. M., 2005. Lehninger

Principles of Biochemistry. 4th Ed., USA, 1057.

18-Bustanji Y., Issa A., Mohammad M., Hudaib M.,

Tawah Kh., Alkhatib H., Almasri I. and Al-Khalidi B.

(2010)."Inhibition of hormone sensitive lipase and

pancreatic lipase by Rosmarinus officinalis extract

and selected phenolic constituents". Journal of

Medicinal Plants,4(21):2235-2242.

19- Osterlund T. (2001). Structure - function

relationships of hormonesensitive lipase. Eur. J.

Biochem., 268: 1899-1907.

21-Tang, W.H., Katz, R., Brennan, M.L., Aviles,

R.J., Tracy, R.P., Psaty, B.M, Hazen, S.L.(2009)

Usefulness of myeloperoxidase levels in healthy

elderly subjects to predict risk of developing heart

failure. Am J Cardiol. May 1;103(9):1269-74.

22-Winterbourn, C.C., Vissers, M. C., Kettle, A.J.,

(2000). Myeloperoxidase. Curr. Opin. Hematol., 7(1),

53.

23-New, K.J., Reilly, M.E., Templeton, K., Ellis, G.,

James, P.E., Mceneny, J., Penney, M., Hooper, J.,

Hullin, D., Davies, B., Bailey, D.M.(2013). Free

radical-mediated lipid peroxidation and systemic

nitric oxide bioavailability: implications for

24-Haberkamp, K., Bondzio, A., Arndt, G.,

Einspanier R, Carstanjen B.(2013). Exercise-induced

alterations in serum myeloperoxidase in

Standardbreds. J Vet Sci. 2013 Jun 28. [Epub ahead

of print]

25-Sugiyama, S., Kugiyama K., Aikawa, M.,

Nakamura, S., Ogawa, H., Libby, P. (2004)

Hypochlorous acid, a macrophage product, induces

endothelial apoptosis and tissue factor expression:

involvement of myeloperoxidase-mediated oxidant in

plaque erosion and thrombogenesis. Arterioscler

Thromb Vasc Biol. Jul;24(7):1309-14

26-Su, M., Stork, C., Ravuri, S. (2001). Sustainedrelease

potassium chloride overdose. J. Toxicol. Clin.

Toxicol. 39 (6): 641–8.

27-Murray, R. K., Bender D. A., Botham K. M.,

Kennelly P. J., Rodwell V.W. (2009). "Harper's

Illustrated Biochemistry". 28 ed. The McGraw-Hill

Companies, p. 891, 111, 236, 267, 162,

28-Woods, D., Hooper, T., Mellor, A., Hodkinson, P.,

Wakeford, R., Peaston, B., Ball, S., Green, N.(2011).

Brain natriuretic peptide and acute hypobaric hypoxia

in humans. J Physiol Sci. 61(3):217-20.

29-Kimber, N.E., Cameron-Smith, D., McGee, S.L.,

Hargreaves, M. (2013). Skeletal muscle fat

metabolism after exercise in humans: influence of fat

availability. J. Appl. Physiol. 114(11):1577-85.

30-Nakamura, M.T., Yudell, B.E., Loor, J.J.(2013).

Regulation of energy metabolism by long-chain fatty

acids. Prog. Lipid Res. pii: S0163-7827(13)00069-6.

31-Moin, S.T., Hofer, T.S., Sattar, R., Ul – Haq, Z.

(2011). "Molecular dynamics simulation of

mammalian 15S-lipoxygenase with AMBER force

filed". Eur. Biophys. J., 40:715-726 .

32-Banerjee, R., Becker, D., Dickman, M.,

Gladyshev, V. and Ragsdale, S. (2008). Redox

Biochemistry. John Wiley and Sons, Inc., Hoboken,

New Jersey. Canada.pp.201-209.

34-Bouzid, M.A., Hammouda, O., Matran, R., Robin,

S., Fabre, C. (2013). Low intensity aerobic exercise

and Oxidative Stress Markers in Older Adults.J

Aging Phys Act. 2013 Nov 13. [Epub ahead of print].