Ultrastructural study for the gonadotrophs and somatotrophs of the pituitary gland in aging rabbits of local bread (oryctolagus cuniculus)
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Abstract
Eighteen rabbit of local bread were classified into3 groups A, B, and C
Group A were 6 rabbits of age one year
Group B were 6 rabbits of age three year
Group C were 6 rabbits of age five year
The whole animals were accomidated for one month before the study, after that the whole animals were exposed to intensive dose of chloroform and then scarified to obtain the pituitary gland by doing anatomical technique EM processing technique. was done and finally the pituitary gland were examined at the anterior lobe ( pars distalis ) to demonstrate the somatotrophes and gonadotrophes ( FSH and LH ) secreting cells .
The present study revealed that somatotrophes and gonado trophes were containing spherical and oval nuclei at one year of age with presence of abundant secretary granules in its cytoplasm associated with Golgi apparatus, these structures were decreased in number and size proportionally with increase of the age of animal at 3 and 5 years .
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References
1- Gomez, Dumm C.L.A, Pucciarelli, H.M, Terreros, MC (1982): Effect of a low – protein diet on the ultra – structure of somatroph cells in the rat. communication Biologicas 1: 165- 170 .
2- Gomez .Dumm C.L.A, Pucciarelli H.M (1987): Quantitative ultrastactural study of Somatotropic cells in undermourished weanling rate . Acta Anatomica . 129: 200-202 .
3- Chen, C.K (2009): Biomarkers in diagnostic head and neck tumor pathology. J , Chiese , Oncol . Soc . 25 (2) 89-101.
4- Hara, M, Herbert, D.C and Taniguchi, T. (1998): Effects of a low – protein diet on prolactin and growth hormone – producing cells in the rat pituitary gland . Anatomical Record 251 : 37 – 43 .
5- Saeger, W. (1992).Effect of drugs on pituitary ultrastructure . Microscope Research Technique. 20 : 162 – 176 .
6- Milosevic, V . Tritunovic, S and Sekulic ( 2006): Estradiol and Calcium affect the growth hormone – producing cells in middle – aged rat females . Acta Veterniaria.2-3 (11) 1- 20 .
7- Herbert, D.C and Carrillo, A.J ( 1982): The hypophyseal – adrenal axis in the protein – Caloric undernourished rat. Hormone and Metabolic Research. 14 : 205 -207 .
8- Console, G.M., Oyhenatt, C, Ferese, C and Gomez Dumm, C.L (2001) : Morphometric and ultrastructural analysis of different pituitary cell population in undernourished monkeys . Brazilian Journal of medical and Biological research. 34 . 65-74 .
9- Mahmoud, M.S and Abdul Hamid, M.(2012): Green tea extract ameliorates liver and pituitary gland toxicity induced by diethy introsamine in male rats. Electron preparation . Journal of American science . 8 (3) .
10 - Esam, B.S., Wafaa, M.Z and Hanan, A-LL .2001: Histological structure and hormonals profile of pituitary and thyroid glands affected by castration and iodine supplementation in male rabbits. Egyptian journal of biology . 3: 38-47.
11 Tanner, J. M (1962): Growth at adolescence Textbook , Blackwell . oxford.
12 Oyhenart, E and Pucciarelli , H.M (1992): Sexual cranial dimorphism in undernourished rats treated with growth hormone. Growth. Development and aging 56: 179-184 .
13 Wilson, D.B and Wyatt, D.P (1988): Growth hormone and prolactin immunoreactivity in the pituitary gland of postnatal little mice . histology and histopathology 1: 309-313 .