Relationship of hepcidin with Iron and lipids in patients with polycystic ovary Syndrome
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Abstract
polycystic ovary Syndrome is a common disorders in the endocrine glands in woman reproductive age the ovary is characterized by the aggregation of small bags surrounded by theca interna layers bloated follicles .
The level of hepcidin and other biochemical parameters were examined in (60) patients with polycystic ovary syndrome attended Azadi and AL-Jumhori in Kirkuk city, in addition to (30) blood samples of healthy individual as control group. The results showed a significant decrease (p <0.01) in the level of hepcidin in addition to the levels of TIBC (p <0.01) with UIBC (p <0.01) and Transferrin (p <0.01) while there was a significant increase in the levels of Iron (p <0.01) and TS% (p <0.01) in patients Compared to healthy control group . The relation was studied between levels of hormone hepcidin and concentration Iron and lipid profile with body mass index the results showed hormone hepcidin decrease in obese women . The results showed Iron increase in the obese group this indicated the rate between, polycystic ovary syndrome and obesity in women for this parameter. The effect of age on patients was studied with hormone hepcidin and iron and lipid profile concentrations where the hormone hipcidin decrease in the duration (15-25) years and increase in duration (26-35) and (36-45) years , The results showed iron and TS% increase in the duration (15-25 years), and decrease in (26-35), (36-45) years, and UIBC showed an increase in (36 -45) years and decreases in the periods (15-25) and (26-35) years either cholesterol and LDL Showing increase in (26-35) years and a decrease in (15-25) and (36-45) .
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